637

2nd ed.

BIOS Scientific Publishers ;Academic Press

2001

xvi, 295 p. ill. 24 cm

The human molecular genetics series

Rev. ed. of: From genotype to phenotype / edited by Steve Humphries, Sue Malcolm. 1994. , Includes bibliographical references and index , Genotype to phenotype: interpretations of the human genome project / Sue Malcolm -- From protein sequence to structure and function / Sylvia B. Nagl -- Genes in population / Fran�cois Cambien -- Gene-environment interaction: lipoprotein lipase and smoking and risk of CAD and the ACE and exercise-induced left ventricular hypertrophy as examples / Steve E. Humpreys, Philippa J. Talmud and Hugh Montgomery -- Pharmacogenomics / Ann K. Daly -- Mitochondrial genetics / P.F. Chinnery and D.M. Turnbull -- Identification of disease susceptibility genes (modifier) in mouse models: cancer and infectious disease / Tom van Wezel, Marie Lipoldova and Peter Demant -- The GNAS1 gene / D.T. Bonthron -- Genomic disorders / Susan L. Christian and David H. Ledbetter -- Genotype to phenotype in the spinocerebellar ataxias / Paul F. Worth and Nicholas W. Wood -- Disorders of cholesterol biosynthesis / David R. Fitzpatrick -- Mutations in the human HOX genes / Frances R. Goodman -- PITX2 gene in development / J. Murray and E. Semina -- The hedgehog pathway and developmental disorders / Allan E. Bale -- X-linked immunodeficiencies / H.B. Gaspar and Christine Kinnon -- The ubiquitin-proteasome system and genetic diseases: protein degradation gone awry / S. Russ Price and William E. Mitch.

Malcolm, Sue. , Goodship, J.